Understanding the Cadet BRAF Test in the Fight Against Canine Bladder Cancer
When our dogs show signs of illness, the worry can be overwhelming. They’re more than pets—they’re family. One of the most frightening possibilities a pet parent can face is cancer, particularly bladder cancer, which can be difficult to detect in its early stages.
Bladder cancer most often affects dogs between 9 and 11 years old and is seen more frequently in certain breeds, including Scottish Terriers, Shetland Sheepdogs, Beagles, West Highland White Terriers, and Wire Fox Terriers. The most common type is transitional cell carcinoma (TCC), a malignant cancer that develops in the lining of the bladder and can spread to other parts of the body. While serious, it is considered relatively uncommon, accounting for about 2% of all canine cancers.
Thanks to advances in veterinary diagnostics, there's now a powerful tool that brings clarity and hope: the Cadet BRAF test. In this article, we’ll explore what the Cadet BRAF test is, how it works, and how it can be a game-changer in the early detection of bladder cancer in dogs.
What Is the Cadet BRAF Test?
The Cadet BRAF test is a cutting-edge, non-invasive screening tool designed to detect transitional cell carcinoma (TCC)—the most common form of bladder cancer in dogs.
Here’s how it works:
What it detects: A specific mutation in the BRAF gene, which is present in the vast majority of dogs with TCC.
How it’s done: A simple urine sample is collected by your veterinarian. The sample is then analyzed for traces of DNA carrying the cancer-related mutation.
Why it matters: Early detection of TCC can make a major difference in the success of treatment and your dog’s quality of life.
The test is especially useful for dogs showing signs of urinary issues—such as blood in the urine, frequent urination, straining to urinate, or recurring urinary tract infections.
What if the Test Is Positive?
A positive result means the BRAF gene mutation has been detected. Here’s what to expect next: